The Healthcare Technology Revolution: Preventative Care and Precision Medicine
November 19, 2025 EST

The healthcare industry stands at an inflection point, with emerging technologies poised to fundamentally reshape how we detect, diagnose, and treat disease.

While recent policy developments have created near-term momentum in healthcare equities, the long-term transformation driven by cutting-edge medical technologies represents a more compelling investment thesis.

A Market Calming After Tariff Concerns

Recent negotiations between the administration and major pharmaceutical companies regarding Most Favored Nation pricing have alleviated some of the acute concerns that weighed on healthcare stocks earlier in the year. While these agreements remain somewhat vague in their specifics, the market's interpretation suggests that revenue impacts will be more modest than initially feared, with some shifting in revenue recognition but without the dramatic disruptions once anticipated.
This stabilization has contributed to improved performance across healthcare sectors, but the more significant story lies in the technological innovations that are changing the fundamental economics and efficacy of healthcare delivery.

The Shift Toward Preventative Care

Perhaps the most underappreciated trend in healthcare is the nascent shift toward preventative medicine. According to research by the Healthcare Cost Institute, preventative services account for only 3.5% of total healthcare spending for individuals with employer-sponsored insurance in 2019, with cancer screenings representing just 1.3% of that total. This remarkably low allocation reflects a healthcare system still predominantly oriented toward reactive treatment rather than proactive prevention.

However, multiple forces are converging to accelerate the transition toward preventative care:

  • Economic Incentives: The shift from fee-for-service to value-based care models creates financial incentives for early detection and intervention. When providers are compensated based on population health outcomes rather than procedure volume, preventing expensive acute care episodes becomes economically advantageous.
  • Technological Capability: Advances in liquid biopsies, AI-enhanced imaging, and genomic analysis are making early detection both more effective and more accessible. These technologies can identify disease states before symptoms manifest, when treatment is most effective and least costly.
  • Artificial Intelligence Integration: AI-powered diagnostic tools are democratizing access to high-quality healthcare recommendations, potentially addressing inequities in care delivery while routing patients toward appropriate preventative services earlier in their health journey.

Leading Technologies Driving Healthcare Transformation

Several technological domains are positioned to capture the increased spending on preventative and precision medicine:

  • Liquid Biopsies: Companies developing blood-based cancer screening technologies represent a paradigm shift in oncology. By detecting cancer signatures in blood samples, these tests enable identification of malignancies at much earlier stages than traditional screening methods. The leading players in this space continue to expand the range of cancers they can detect and improve their accuracy rates, driving increased clinical adoption and insurance coverage.
  • Surgical Robotics: Minimally invasive robotic surgical systems are gaining market share across multiple specialties, including orthopedics (knee and hip procedures), general surgery, and other applications. These systems offer improved precision, faster patient recovery times, and better outcomes compared to traditional open surgery approaches.
  • AI-Enhanced Imaging: Artificial intelligence is transforming radiology and diagnostic imaging by making CT scans, MRIs, and ultrasounds faster, more accurate, and more accessible. AI algorithms can identify subtle patterns that might escape human observation, leading to earlier detection of abnormalities and more confident diagnoses.
  • Gene Editing and RNAi Technologies: Precision medicine approaches, including gene editing and RNA interference therapies, are moving from theoretical possibilities to clinical realities. These technologies enable targeted treatment of genetic disorders and diseases at the molecular level, representing a fundamental departure from the blockbuster drug model that has dominated pharmaceutical development.
  • Regenerative Medicine and Process Automation: Laboratory automation and advanced manufacturing techniques are accelerating the development and production of cell therapies and other regenerative medicine approaches, while reducing costs and improving quality control.

A Research-Driven Approach to Healthcare Innovation

Rather than simply tracking large pharmaceutical companies facing patent cliffs on blockbuster drugs, a technology-focused healthcare strategy identifies and weights companies addressing specific societal challenges: aging populations, rising healthcare costs, and the need for more accessible and effective treatments.

This research-driven methodology enables overweighting companies leading in critical areas that are reshaping healthcare delivery. By focusing on the innovators developing and commercializing next-generation medical technologies, investors gain exposure to companies that other broad healthcare indices may underweight or exclude entirely.

The Two Pillars of Future Healthcare

The evolution of healthcare increasingly revolves around two complementary principles:

  1. Preventative Focus: Identifying and addressing health issues before they become acute, expensive problems
  2. Precision Medicine: Delivering the right treatment to the right patient at the right time, based on individual genetic, environmental, and lifestyle factors.

This represents a significant departure from the current model of reactive, one-size-fits-all medicine. As spending patterns shift to align with these principles—a transition we expect will accelerate over the next decade—companies positioned at the forefront of these technologies should see sustained demand growth.

Real-World Impact and Expanding Applications

The technologies driving this transformation are not speculative concepts but proven solutions with expanding real-world applications. Liquid biopsy companies continue to receive expanded coverage for additional cancer types, surgical robots demonstrate improved outcomes in clinical studies, and AI imaging tools are being integrated into standard clinical workflows.

This momentum is reflected in improved reimbursement decisions, increased clinical adoption, and growing evidence bases supporting the efficacy of these interventions. The feedback loop between technological advancement, clinical validation, and commercial adoption is accelerating.

Conclusion

While near-term policy developments create trading opportunities in healthcare stocks, the long-term investment case rests on fundamental technological innovation. Healthcare technology companies are developing and commercializing solutions that address critical societal needs: reducing costs, improving outcomes, and expanding access to high-quality care.

The shift toward preventative care and precision medicine represents a multi-decade transformation in how healthcare is delivered. Companies leading this transition—in liquid biopsies, surgical robotics, AI diagnostics, genomics, and regenerative medicine—are positioned to capture an increasing share of healthcare spending as the industry evolves beyond the legacy pharmaceutical model toward a more proactive, personalized, and technologically sophisticated approach to human health.

 


 

Carefully consider the Funds’ investment objectives, risk factors, charges and expenses before investing. This and additional information can be found on the Funds' full or summary prospectuses, which may be obtained at www.roboglobaletfs.com. Read the prospectus carefully before investing.

Investing involves risk, including the possible loss of principal. International investments may also involve risk from unfavorable fluctuations in currency values, differences in generally accepted accounting principles, and from economic or political instability. Emerging markets involve heightened risks related to the same factors as well as increased volatility and lower trading volume. Narrowly focused investments and investments in smaller companies typically exhibit higher volatility. There is no guarantee the funds will achieve their stated objective. ROBO and HTEC are diversified. THNQ is non-diversified.

The liquidity of the A-shares market and trading prices of A-shares could be more severely affected than the liquidity and trading prices of other markets because the Chinese government restricts the flow of capital into and out of the A-shares market. The funds may experience losses due to illiquidity of the Chinese securities markets or delay or disruption in execution or settlement of trades.

The risks associated with investments in Robotics and Automation Companies include, but are not limited to, small or limited markets for such securities, changes in business cycles, world economic growth, technological progress, rapid obsolescence, and government regulation. Robotics and Automation Companies, especially smaller, start-up companies, tend to be more volatile than securities of companies that do not rely heavily on technology. Rapid change to technologies that affect a company's products could have a material adverse effect on such company's operating results. Robotics and Automation Companies may rely on a combination of patents, copyrights, trademarks and trade secret laws to establish and protect their proprietary rights in their products and technologies. There can be no assurance that the steps taken by these companies to protect their proprietary rights will be adequate to prevent the misappropriation of their technology or that competitors will not independently develop technologies that are substantially equivalent or superior to such companies' technology.

The risks associated with Artificial Intelligence (AI) Companies include, but are not limited to, small or limited markets, changes in business cycles, world economic growth, technological progress, rapid obsolescence, and government regulation. Rapid change to technologies that affect a company’s products could have a material adverse effect on such company’s operating results. AI Companies also rely heavily on a combination of patents, copyrights, trademarks and trade secret laws to establish and protect their proprietary rights in their products and technologies. There can be no assurance that the steps taken by these companies to protect their proprietary rights will be adequate to prevent the misappropriation of their technology or that competitors will not independently develop technologies that are substantially equivalent or superior to such companies’ technology. AI Companies typically engage in significant amounts of spending on research and development, and there is no guarantee that the products or services produced by these companies will be successful.

The risks associated with Medical Technology Companies include, but are not limited to, small or limited markets for such securities, changes in business cycles, world economic growth, technological progress, rapid obsolescence, and government regulation.

Diversification may not protect against market risk.

Beginning September 2, 2020, market price returns are based on the official closing price of an ETF share or, if the official closing price isn't available, the midpoint between the national best bid and national best offer (“NBBO”) as of the time the ETF calculates current NAV per share. Prior to September 2, 2020, market price returns were based on the midpoint between the Bid and Ask price. NAVs are calculated using prices as of 4:00 PM Eastern Time. The returns shown do not represent the returns you would receive if you traded shares at other times.

The Funds are distributed by SEI Investments Distribution Co. (SIDCO) 1 Freedom Valley Drive, Oaks, PA, 19456